Advanced genomics and gene expression - SMB0002

Assessment 1: Other

To be as SENDA-compliant as possible, students will be assessed via a broad range of methods to provide an opportunity to demonstrate achievement of the LOs in alternative ways. Student PLSP will be consulted and where required reasonable adjustments will be made to assessments in consultation with Disability Support.

Assessment Strategy

Assessment 2: Other

Individual (LO1, 3 and 4) and group (LO2) formative assessment will be made available via the VLE. Formative assessment of LO5 and 6 will be via group workshop discussions and live polling software.    

Formative assessment

Assessment 1: Presentation

Presentation

Assessment 2: Presentation

Our understanding of the human genome and how it is expressed has undergone a seismic shift in the past decade. This module will explore our modern understanding of 3D-genomes and how this relates to the complexities of transcriptional activation, post-transcriptional processing of RNA both in the nucleus and cytoplasm, and the explosion of non-coding RNA as regulators of our genes. Also, translation, a process long-thought to be primarily mechanistic, will be discussed in terms of emerging regulation via tRNA-fragments and specialised ribosomes.

School of Applied Sciences

Molecular biology of the cell
Alberts, Bruce, Wilson, John H., Hunt, Tim,6th edition. Abingdon, UK :Garland Science Taylor and Francis Group
 
In addition suggested and directed reading will be provided as part of lecture content

Biomedical & Life Sciences

SMB0002 - Advanced genomics and gene expression

Advanced genomics and gene expression

be able to synthesise understanding as it relates to the structure and function of the human genome.

be able to demonstrate competency in the articulation of complex concepts to a non-expert audience.

be able to synthesise how transcription and translation are regulated in humans.

be able to synthesise an overview of the selected topic via online media.

be able to illustrate how non-coding RNA impacts on gene expression.