Drug Design and Development - SMP4007

Assessment 1: Oral presentation/assessment

Formative assessment will include short seminar presentations to their peers and a visiting industrial expert on their product development, encouraging further discussion and thought generation.

Oral presentation/assessment

Assessment 3: Exam

Exam

Assessment 1: Project Work

Project work comprises an extended formulation development report (25%) and an oral presentation (5%). This will include information gathered and studied from a wide range of literature sources as well as from current practitioners from relevant areas. The proposed formulation will be presented as a seminar and will then be prepared in the laboratory and appropriate quality tests applied.
Report &#61; 3000 words
 

Project Work

Formulation Design and Development

SMP0001 - Formulation Design and Development

The aim of this module is to provide an in-depth appreciation of all the stages from new drug identification to bringing a drug to the market and beyond, with an emphasis on biotechnology-based products. It is divided into two integrated streams, the first being drug design. Students will gain a critical appreciation of drug design and methods of discovery (chemical synthetic, biotechnological, mineral and plant origin and other natural sources). Drug development will include pre-clinical, clinical and post-marketing surveillance aspects. The incorporation of advanced drug delivery strategies into current practice and future directions will be covered in detail.  Material will illustrate the influence the drug development and delivery bears on the armaments available to healthcare practitioners to treat disease.  Students will be expected to integrate and apply their knowledge and skills in the development of their own formulation supported by representatives from the pharmaceutical industry.

School of Applied Sciences

<a href="https://library.hud.ac.uk/readinglists/SMP4007">https://library.hud.ac.uk/readinglists/SMP4007</a>

Aulton and Taylor (2018) Aulton's pharmaceutics: the design and manufacture of medicines, ISBN: 9780702070051
Patrick G L., (2017) An introduction to medicinal chemistry, ISBN: 9780198749691
Flaherty D K. (2012) Immunology for Pharmacy, ISBN: 0323069479
Florence A T., (2016) Physicochemical principles of pharmacy, ISBN: 0857111744
Cottrell S., (2013) The study skills handbook - Chapter: 10: Working with Others: Collaborative Study, ISBN: 9781137289254

Pharmacy

SMP4007 - Drug Design and Development

Drug Design and Development

Critically assess the drug discovery, design, development and manufacture of medicines with reference to current practice.

Critically appraise the benefits and challenges associated with drugs from biotechnology origins and future directions. 

Appreciate and debate how a drug’s key features predict its reactivity, action, physico-chemical, chemical compatibilities, degradation and stability.


Actively take part in the management of risks during drug design and formulation development considering their impact on people.

Appreciate role of targeted therapies in future medical practice.

Correlate pharmaceutical principles with a literature survey to propose viable formulations, to orally describe and defend the proposed product and development profile and to manufacture it.

Critically appraise drug and formulation design strategies with reference to key principles, approaches and potential future developments in major therapeutic areas.

Evaluate and make distinctions on all the stages involved in drug development and the methods used to ensure efficacy of medicines and biopharmaceuticals. 