Pharmaceutical Formulation and Drug Analysis - SHB4017

Assessment 1: Written practice exercise

In tutorial sessions, model questions will be discussed and students will develop their problem-solving skills.

Written practice exercise

Assessment 2: Exam

Exam

Assessment 1: Practical Skills Assessment

Assessment will comprise practical reports based on experimental formulation and analysis of products. The workshop will require them to apply pharmaceutical knowledge into practice. 
Practical 18 hours.
Workshop 6 hours.

Practical skills assessment

Pharmaceutical Formulation and Drug Analysis

SHP3005 - Pharmaceutical Formulation and Drug Analysis

<p>This module will extend the student’s understanding of pharmaceutics and biopharmaceutics and relevance to an extended range of dosage forms. Different delivery methods, routes of delivery and formulation type will be individually reviewed including oral and aerosol formulations. Formulation approaches to targeting the different routes of delivery (buccal, colon, rectal, nasal ophthalmic, pulmonary and transdermal) will also be covered. The structure and the nature of the barrier properties of the tissue will be discussed in terms of the advantages afforded by delivery to the site and strategies for maximising absorption. The design, manufacture and performance of modified release drug dosage forms and factors governing release kinetics from reservoir, osmotic and monolithic systems and mathematical calculations will be covered.  Aspects of formulation and the importance of pharmaceutical analysis to maintain the quality, safety and efficacy of the product will be consolidated in the practicals and case-study.  Pharmaceutical analysis including thermal, and rheological analyses are covered along with release testing, UV analysis, aerosol testing and particle sizing.</p>

School of Applied Sciences

<p><a href="https://library.hud.ac.uk/readinglists/SHB4017">https://library.hud.ac.uk/readinglists/SHB4017</a></p>

Biomedical & Life Sciences

SHB4017 - Pharmaceutical Formulation and Drug Analysis

be able to develop and apply the principles of biopharmaceutics which control the bioavailability of drugs from their delivery devices.

be able to use theoretical models to understand physicochemical properties, to assess the validity of quantitative data, undertake appropriate mathematical analysis competently and to be able to develop a rationale to explain such results.

compare the analytical techniques routinely used in the testing of pharmaceuticals.

debate the advantages and disadvantages of the major dose forms including modified-release formulations.

be able to demonstrate a detailed understanding of formulation requirements, which are important in the design, manufacture and quality assurance, of a range of pharmaceutical dosage forms.

be able to understand, recognise and assess the strategies available for the design of modified-release drug delivery systems.

be able to correlate the physicochemical and pharmaceutical properties of   medicinal compounds with the requirements necessary to design effective delivery systems.

be able to experimentally investigate analytical methods and formulation development.

appraise the role of formulation in dosage forms.