Please note

This document only provides information for the academic year selected and does not form part of the student contract

School:

School of Applied Sciences

Credit Rating:

20

Level (including FHEQ):

F (FHEQ Level 4)

Graded or Non Graded:

Graded

Version Valid From:

2023-09-01

Module Leader:

Anna Murphy

Version Number

2023.05

Learning Methods

Guided Independent Study

Lecture

Practical Classes and Demonstrations

Seminar

Synopsis

The module will introduce students to the fundamental concepts of pharmacology. The four main types of regulatory proteins (receptors, enzymes, transporters and ion channels) are discussed as potential drug targets in various organ systems. The physical processes of drug absorption and distribution around the body is discussed, followed by a … For more content click the Read More button below. Students will be introduced to competitive antagonism. Desensitisation and tolerance will be discussed with relevant examples.  

Learning Strategy

Lectures and tutorials will be used to deliver the material. Tutorials including lab demonstrations will reinforce salient points in lectures and develop problem solving and investigative skills.  Tutorials will also be used to support their oral and presentation skills and directed study time will ensue through preparation. The laboratory and … For more content click the Read More button below.

Outline Syllabus

Chemical principles relevant to pharmacologyPharmacokinetics and kinetic models of clearance.Aetiology and epidemiology of major diseases and principles of drug action.Antagonism, including competitive antagonism, non-competitive antagonism, reversible competitive antagonism.Laboratory and computer studies to highlight the effect of drugs in the cardiovascular, haematological and respiratory systems.  

Learning Outcomes

On successful completion of this module students will
1.
discuss drug action in the various organ systems, as well as in relation to inflammatory and microbial infections using specific examples of diseases.
2.
describe the principles and application of pharmacokinetics, in the provision of safe and effective treatment.
3.
demonstrate knowledge of various protein targets for drug binding.
4.
understand mechanisms of desensitization and tolerance.
5.
understand the relation between drug concentration and effect.
6.
understand the distinction between drug binding and receptor activation, with reference to rate constants.
7.
apply knowledge of the principles of drug action in simulated and real laboratory procedures to investigate pharmacological phenomena.
8.
discuss the factors that affect the rates at which drugs are absorbed, distributed, metabolized and excreted, giving pertinent examples.
9.
demonstrate an awareness of the various kinetic models of drug clearance and solve simple problems.
10.
undertake structured problem solving and show accuracy in pharmaceutical calculations.
11.
Make use of pharmacological simulation software, library and electronic information resources including the use of databases and spreadsheets for data analysis.

Formative Assessment

Assessment 1: Quizzes / polls

Summative Assessment

Assessment 1: Written Assignment

Assessment 2: Written Assignment

Assessment 3: Exam

Assessment Criteria

The module handbook will provide additional guidance for students on the specific assessment criteria and marking schedules applied to individual pieces of work. Practical competency will be assessed in class by teaching staff.

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