Targeted Synthesis of Organic Compounds - SMC4002

Assessment 1: Practical skills assessment

Informal feedback will be given in the tutorial sessions which will place an emphasis on developing problem solving skills.

Formative assessment

Assessment 2: Exam

Exam

Assessment 1: In-Class Test

In-Class Test

Assessment 3: Practical Skills Assessment

Practical Skills Assessment

Organic Chemistry 3

SHC4002 - Organic Chemistry 3

This module draws together the basic concepts of synthesis and reaction mechanisms in the context of providing methods for designing suitable synthetic routes to target compounds and also extends the range of reaction types to include pericyclic reactions.
The module introduces contemporary preparative methods for the synthesis of organic compounds.  Further aspects relating to designing a synthesis and the connection between design and retrosynthetic principles are covered.  The selectivity of reactions and the concepts of regio-, chemo-, stereo- and enantioselectivity are developed and expanded as are the rules governing pericyclic reactions.
The reaction mechanism component draws together concepts in both physical and mechanistic organic chemistry; this section of the course covers those techniques that can be used to differentiate between mechanistic types.  The use of product analysis, activation parameters, linear free energy relationships and isotope effects to determine reaction mechanisms are included.

School of Applied Sciences

<a href="https://library.hud.ac.uk/readinglists/smc4002">https://library.hud.ac.uk/readinglists/smc4002</a>

Container 1

Chemical Sciences

SMC4002 - Targeted Synthesis of Organic Compounds

Targeted Synthesis of Organic Compounds

be able to design highly selective routes to novel organic compounds using retrosynthetic analysis;.

be able to devise experiments to test hypotheses of reaction mechanisms and be able to propose solutions to mechanistic problems generated within a research environment.

be able to have a knowledge and an understanding of contemporary methods used in the synthesis of known and novel organic compounds including the use of pericyclic reactions and reactions involving radicals and carbenes as intermediates.

be able to have a systematic knowledge of the techniques of physical organic chemistry and their application in a research environment.

able to design synthetic routes using contemporary methods.

be able to have a knowledge of the principles involved in applying retrosynthetic analysis and its application in the design of synthetic routes that are regio-, chemo-, stereo- and enantioselective.